Similarly, in uveal melanoma (UVM) and liver hepatocellular carcinoma (LIHC), CRABP2 expression is significantly correlated with seven of these immune checkpoint genes (LAG3, CTLA4, PDCD1LG2, HAVCR2, PDCD1, CD274, and TIGIT). The gene discussed is HAVCR2; the disease is uveal melanoma.