Using two metabolites from gastric cancer cells (Hgc27 and MKN45) to affect M0 macrophages, in M1 marker detection, the metabolites from gastric cancer cells (Hgc27 and MKN45) showed high similarity with IL-4 and TGFβ1, confirming the correctness of the conclusion that gastric cancer cell metabolites can promote more M0 macrophages to polarize towards M2 type. Here, IL4 is linked to gastric cancer.