The results showed that MCM3 was significantly overexpressed in cholangiocarcinoma (CHOL), Colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), LIHC, Lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), rectum adenocarcinoma (READ), stomach adenocarcinoma (STAD) and other cancers (Figure 1A). This evidence concerns the gene MCM3 and carcinoma of esophagus.