The number of ITGAM-, ITGB2-, ICAM-3- and ICAM-3/ITGB2-positive cells was significantly increased (p < 0.0001 to p < 0.04), and a positive correlation was observed between the number of ICAM3/ITGB2- and ITGAM-positive cells in CRSwNP (p < 0.02), compared to controls. This evidence concerns the gene ITGB2 and chronic rhinosinusitis with nasal polyps.