The AUC of the combined EGF and sTREM-1 levels test for predicting a patient's prognosis was greater than that of sTREM-1 alone (P<0.05).<h4>Conclusions</h4>In short, age (>55 years), smoking, poor oral hygiene, and oral PH<7 are risk factors for RIOM for NPC. The gene discussed is EGF; the disease is nasopharyngeal carcinoma.