The diagnostic sensitivity and specificity of GLUT4, LEPR, and TNF-α combined assay for PCOSinduced infertility in PCOS women were 88.57% and 75.00%, respectively, and those for PCOS in healthy women were 78.57% and 60.00%, respectively (P<0.05). The gene discussed is LEPR; the disease is polycystic ovary syndrome.