At the same time, LEPR and TNF-α were negatively associated with endometrial thickness and positively correlated with RI and PI (P<0.05).<h4>Conclusions</h4>GLUT4, LEPR, and TNF-α are closely related to ER in patients with PCOS-induced infertility, and their combined detection can effectively evaluate the occurrence of PCOS and PCOS-induced infertility. Here, SLC2A4 is linked to polycystic ovary syndrome.