With the deepening research on the pathogenesis of PCOS and its chronic inflammatory state, it has been found that a variety of signaling pathways are involved in the initiation and progression of inflammation (222), among which the more important ones such as PI3K/AKT, MAPK, and AMPK signaling pathways, and the SCFAs have anti-inflammatory roles in PCOS, but these signaling pathways have been reported less frequently in the study of SCFAs. This evidence concerns the gene AKT1 and polycystic ovary syndrome.