Expression levels of Pcna, Ccnd1(CyclinD1), Bcl2, Itga2, Itgb1, Fak, Pik3r1, Akt1, Mtor and Myc were remarkably upregulated and Bax was downregulated in colonic tumors of mice treated with S. moorei (Figure S4A). This evidence concerns the gene ITGA2 and colonic neoplasm.