ITGAM and neoplasm: Oxysterol-CXC chemokine receptor 2 (CXCR2) axis plays a key role in the recruitment of tumor-promoting CD11b+Gr-1+ myeloid cells, and flow cytometry revealed an increase in the number of CXCR2 Mo-MDSCs, which in turn enhances innate immunosuppression and tumor progression 91.