When we performed a linear model with either ENA-78/CXCL5 or GRO-α as response variables and R&E, cachexia status, stage, sex, and BMI as predictor variables, NHB demonstrated significantly increased ENA-78/CXCL5 and GRO-α/CXCL1 compared to other R&E groups (Table S10). This evidence concerns the gene CXCL1 and Cachexia.