The genes, mainly PDGFRB[51], TRIM28[52], MME[53], IRF4[54], KRT18[55], RIPK11[56], CXCR55[57], and OUTB1,[58] were consistently inherited from F0 and F1 germlines by the livers of F2 females, suggesting their potential role in promoting the NAFLD-NASH phenotype. This evidence concerns the gene IRF4 and metabolic dysfunction-associated steatotic liver disease.