The analysis revealed that VTN, OTUB1, ADIPOR2, CAT, BIRC5, CXCR5, and RIPK1 were linked to the NASH phenotype, whereas TRIM8, DIO1, TRIM28, and PDGFRB were associated with NAFLD in F2 female livers (Fig. 3C). This evidence concerns the gene TRIM8 and metabolic dysfunction-associated steatotic liver disease.