Several cytokines (TNF, IL-1β) and chemokines (CXCL10, CCL2, CCL5) were reduced in the brains of Rag1–/– animals at day 14 after infection, which were restored or exceeded WT levels mainly with Th1 adoptive transfer, whereas Th17 cells were less effective (Figure 4H). This evidence concerns the gene IL1B and infection.