IFNGR1 and infection: Conversely, IFN-γ receptor 1 (IFN-γR1; CD119) blockade in Il17a/f–/– mice exacerbated infectious burdens in the brain and galea compared with isotype-treated Il17a/f–/– animals (Figure 10C) confirming the cooperativity between the 2 cytokines and a dominant role for IFN-γ in infection containment.