Oil Red O staining showed that Betulin treatment significantly reduced the level of tissue lipid droplets (Fig. 9G, H), and Ki-67 staining indicated that Betulin and docetaxel treatment alone inhibited tumor proliferation, with the combination of Betulin and docetaxel showing a stronger inhibitory effect (Fig. 9I, J). This evidence concerns the gene MKI67 and neoplasm.