METTL3 and gastric cancer: In our recent research, we found that exosomal Thrombospondin 1 (THBS1) derived from gastric cancer (GC) cells regulates METTL3- or IGF2BP2-mediated m6A modification, activating the RIG-I-like receptor signaling pathway in Vγ9Vδ2 T cells, thereby enhancing their cytotoxicity against GC cells [82].