In our recent research, we found that exosomal Thrombospondin 1 (THBS1) derived from gastric cancer (GC) cells regulates METTL3- or IGF2BP2-mediated m6A modification, activating the RIG-I-like receptor signaling pathway in Vγ9Vδ2 T cells, thereby enhancing their cytotoxicity against GC cells [82]. The gene discussed is IGF2BP2; the disease is gastric cancer.