The 1,026 DEGs specifically upregulated in the non-regression group were also significantly enriched in the “p53 signaling pathway.” Intriguingly, 1,314 DEGs specifically upregulated in the regression group were highly enriched in a variety of immune response-related pathways, including “positive regulation of lymphocyte activation” and “immune response-activating cell surface receptor.” Thus, the immune response appears to be linked to p53 rescue-triggered tumor regression. This evidence concerns the gene TP53 and neoplasm.