PSRC1 and coronary artery disorder: Only the gene PSRC1 expressed in whole blood showed colocalization with CAD (PP.H4 = 0.9935), which indicated therapeutic potential of PSRC1 overexpression for CAD together with its negative causal association, and the shared causal variant was identified as rs7528419, while the other 11 genes all obtained PP.H3 greater than 0.8952, indicating distinct causal variants at these loci (Figure 4B; Table S15, Supporting Information).