We identify the association of PEAK1 with calcium/calmodulin-dependent protein kinase 2 (CAMK2)D and CAMK2G, of particular interest given the known roles of specific CAMK2 isoforms in many human cancers, including breast cancer, and the therapeutic ‘actionability’ of these serine/threonine kinases20,21. The gene discussed is CAMK2D; the disease is breast cancer.