Adiponectin is influenced by sex, diabetes status, and adiposity (visceral vs subcutaneous adipose tissue), while NT-proBNP is affected by age and sex,30 race,36 and BMI (ie, lower in individuals with higher BMI),37 and cutoffs for categorical analysis were based on clinical thresholds26 rather than population-specific thresholds. Here, NPPB is linked to diabetes mellitus.