Gnoni et al.(2022) reported quercetin significantly reduces the expression of SREBP-1and XBP-1 genes, and their lipogenic gene targets, and has a direct anti-lipogeniceffect. There is a close relationship between obesity and reproductive systemfunction in women. The study of Soleimani Mehranjaniet al. (2021) has shown that quercetin can improvethe tissue quality and function of mouse ovaries. Quercetin has been found to havegenomic actions regulating the expression of several genes (Ghafouri-Fard et al., 2021). This evidence concerns the gene XBP1 and obesity due to melanocortin 4 receptor deficiency.