This explains thehigh LH/FSH ratio and the large levels of androgens in these women, and also thepossibility of a positive feedback loop between AMH, LH, and GnRH in PCOS (Rudnicka et al., 2021).Because of the close relationship between serum AMH levels and preantral and antralovarian follicle counts on ultrasound, AMH has been advocated as an alternativediagnostic criterion, particularly in circumstances when ultrasound examination ofthe ovaries is challenging (Rudnicka etal., 2021). This evidence concerns the gene BRD2 and polycystic ovary syndrome.