The mean pooled PR of CSI was 49% (95% CI, 9%-90%, 3 studies, 12 participants, I2 0%, 95% PrI 0%-100%, very low quality of evidence) and 36% (95% CI, 12%-71%, 5 studies, 39 participants, I2 44%, 95% PrI 3%-92%, very low quality of evidence) for PIT1+/H− and PIT1+/H+ adenomas, respectively. This evidence concerns the gene POU1F1 and adenoma.