The most interesting differentially expressed cardiac genes are CACNA2D1, CASQ2, CDH2, DSC2, DSP, GJA5, GPD1L, KCNE3, LAMA4, MYOZ2, NEXN, SCN4B, SDHA, SLMAP and SNTA1, as mutations in these genes have been reported in ion channelopathies or cardiomyopathies [48, 49]. Here, KCNE3 is linked to cardiomyopathy.