Further establishing the link between c‐MYC/MYCN and ATP13A3 would be very promising as such observations have been reported in pancreatic cancer cells where the correlation between expression levels of c‐MYC, ATP13A3 and polyamine uptake appear to predict the cells' responsiveness to polyamine depletion therapy (i.e., DFMO + a polyamine transport inhibitor such as AMXT 1501) [31]. This evidence concerns the gene MYCN and familial pancreatic carcinoma.