Many studies have explored the regulatory mechanism of lncRNA HOXC13-AS in different types of cancer (Figure 5), including nasopharyngeal carcinoma (Gao et al., 2019), breast cancer (Li et al., 2019a), oral squamous cell carcinoma (Li et al., 2020), glioma (Liu et al., 2019), and cervical cancer (Wang et al., 2021). This evidence concerns the gene HOXC13 and central nervous system cancer.