Mechanistically, HOXC13-AS acts through the HOXC13-AS–miR-383-3p–high mobility group AT-hook 2 (HMGA2) axis, where HOXC13-AS functions as a ceRNA and promotes NPC progression by competitively sponging with miR-383-3p to enhance the expression of HMGA2 (Gao et al., 2019). This evidence concerns the gene HMGA2 and nasopharyngeal carcinoma.