Similar to our results, influenza was shown to employ clathrin-coated vesicles as a non-exclusive mode of entry into cells (Bao et al., 2021; Lakadamyali et al., 2004; Mazel-Sanchez et al., 2023; Rust et al., 2004; Sun and Whittaker, 2013), but inhibition of clathrin-mediated endocytosis via expression of the Δ95-295 mutant of Eps15 or chlorpromazine failed to inhibit influenza infection in HeLa cells (Sieczkarski and Whittaker, 2002). The gene discussed is EPS15; the disease is influenza.