Exceptions include: eotaxin (chemoattractant of eosinophiles) (27) increased in the lymph nodes and spleen, lipopolysaccharide-induced CXC chemokine (LIX; cell migration and activation of neutrophiles) (28), granulocyte-macrophage colony-stimulating factor (GM-CSF; development, differentiation and activation of macrophages and granulocytes) (29) and monokine induced by IFN-γ (MIG; chemokine recruiting activated T cells to infection site) (30) increased in the spleen. The gene discussed is CSF2; the disease is infection.