Hyperthyrotropinemia (TSH > 5 μIU/mL) increased the risk of dyslipidemia (OR 3.96, 95%CI, 1.17–13.28, p = 0.027), but the presence of both anti-TPO-Ab or Tg-Ab was not associated with the risk of dyslipidemia. This evidence concerns the gene TPO and metabolic syndrome.