Furthermore, LASSO Cox regression analysis identified 10 genes (SP110, HHAT, TUBB, MORC4, TERT, PPARG, MAP3K5, PAGE5, MAP7, and CAMK1G) that exhibited a remarkable correlation with the prognosis of osteosarcoma patients (Figure 1B, minimum lambda value). This evidence concerns the gene MAP3K5 and osteosarcoma.