GH1 and Laron syndrome: Besides growth failure, the case with IGHD revealed a doll face, truncal obesity, frontal bossing, and acromicria without psychomotor development defect, whereas the patient with Laron Syndrome presented with a large head, saddle nose, cranium hypoplasia, underdeveloped mandible, protruding forehead, and a micropenis with high GH levels [20].