Children in the MAFLD group had higher levels of fasting insulin (FINS), HOMA-IR, fasting C-peptide, leukocyte (WBC), HbA1c, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) compared to the simple obesity group. The gene discussed is INS; the disease is obesity due to melanocortin 4 receptor deficiency.