Snail family zinc finger 1 (SNAI1) is the first and most extensively studied E-cadherin transcriptional repressor, and E-cadherin, encoded by the epithelial gene CDH1, is a marker of epithelial-mesenchymal transition (EMT), a developmental process that cancer cells use to promote invasion, metastasis, and therapy resistance (47). This evidence concerns the gene SNAI1 and cancer.