The results showed that some HOX genes in pan-cancer had significant strong correlation (R≥0.8; Figures 2C–F): HOXA9 with HOXA10, HOXB5 with HOXB6 and HOXB8, HOXB8 with HOXB6 and HOXB9, HOXB3 with HOXB4 and HOXB5 and HOXB6, HOXC8 with HOXC9, HOXC9 with HOXC10, HOXD10 with HOXD11. This evidence concerns the gene HOXB3 and cancer.