ESR1 and carcinoma: A core-needle biopsy was performed, and histologic examination revealed: for the 23 mm lump, a No Special Type Invasive Carcinoma, Grade 3, Estrogen Receptor 0%, Progesterone Receptor 0%, Ki67 39% HER2 score 0; for the 20 mm nodule, a No Special Type Invasive Carcinoma, Grade 3, Estrogen Receptor 5%, Progesterone Receptor 0%, Ki67 65% HER2 score 0.