BSCL2 and Insulin resistance: Interestingly, pAKT levels were significantly elevated in Seipin−/− mice at 48 and 72 h after PHx compared with WT mice, suggesting that the impaired liver regeneration observed in Seipin−/− mice may not be due to insulin resistance, although we cannot rule out the potential negative effect of pre‐existing insulin resistance in Seipin−/− mice.