Furthermore, our data indicated that overexpression of METTL1 enhances abemaciclib, a CDK4/6 inhibitor, which targets the RB1 tumour suppressor protein and causes G1/S phase cell cycle arrest in tumour cells, and the combined treatment of abemaciclib with METTL1 lentivirus (LV‐METTL1) is more effective at inhibiting tumour growth than either treatment alone.38 The gene discussed is RB1; the disease is neoplasm.