Women who attended religious services on holidays (HR = 0.61, 95% CI: 0.43–0.88), once per week (HR = 0.65, 95% CI: 0.45–0.95) and more than once per week (HR = 0.60, 95% CI: 0.41–0.89) had significant 35–40% reduced hazards from all-cause mortality compared to those who never attended religious services at all, adjusting for age at BC diagnosis, race, time from cohort enrollment to diagnosis, income, education, marital status, insurance, HER2, tumor ER and PR status However, addition of treatment and cancer stage in the fourth model attenuated this association. The gene discussed is ESR1; the disease is breast cancer.