AKT1 and cervical cancer: In addition, targeting enzymes involved in specific lipid metabolic pathways represents a promising avenue for the development of novel therapeutic strategies to treat cervical cancer LNM.463 In a recent study, Mei et al. demonstrated that 7-dehydrocholesterol reductase (DHCR7) plays a crucial role in promoting LNM by activating the KANK4/PI3K/AKT signaling pathway and enhancing VEGF-C secretion.