Conversely, in several cancers—including GBM, head and neck squamous cell carcinoma (HNSC), lung squamous cell carcinoma (LUSC), skin cutaneous melanoma (SKCM), and UCS—HOXD13 was highly expressed in tumors but exhibited low or absent expression in the corresponding normal tissues. The gene discussed is HOXD13; the disease is squamous cell lung carcinoma.