All infected FVB/N mice (20/20) challenged with cerebellum showed the same characteristic pattern of PrP deposition and diglycosylated PrP dominant PrPSc type (Fig 4C) as seen in transmissions of frontal cortex, parietal cortex and thalamus from the 129MV vCJD patient to the same mice. The gene discussed is PRNP; the disease is variant Creutzfeldt-Jakob disease.