Grade 3 or higher TRAEs observed in 5% or more of patients included anemia (13 patients [26%]), hematuria (5 patients [10%]), lymphocytopenia (4 patients [8%]), alanine aminotransferase elevation (3 patients [6%]), and aspartate aminotransferase elevation (3 patients [6%]) (Table 1; eTable 2 in Supplement 2). This evidence concerns the gene GPT and anemia (phenotype).