SIRT1 expression levels resulted also correlated positively with the expiration/inspiration ratio (p = 0.016; r = 0.362) and with deep breathing (p = 0.005; r = 0.419), while VDR expression levels correlated negatively with the orthostatic hypotension (p = 0.049; r = − 0.279). This evidence concerns the gene SIRT1 and hypotensive disorder.