In the Tisle+GC group, the most common nonhematologic AEs were elevated aspartate amino transferase (AST; 13.24% for all grades, 1.47% for grade ≥ 3), hyponatremia (11.76% for all grades), elevated alanine amino transferase (ALT; 10.29% for all grades), and high uric acid (10.29% for all grades). This evidence concerns the gene GPT and Hyponatremia.