To explore the biological role of CD2BP2‐DT in breast cancer cells, we designed two siRNAs (si‐CD2BP2‐DT#1 and si‐CD2BP2‐DT#2), one shRNA (sh‐CD2BP2‐DT) targeting CD2BP2‐DT, and an overexpression plasmid. The gene discussed is CD2BP2; the disease is breast carcinoma.