To further explore the specific binding site of CD2BP2‐DT with YBX1, we utilized RNAfold software to predict the secondary structure of CD2BP2‐DT (Figure S3D, Supporting Information) and created a biotinylated full‐length CD2BP2‐DT construct along with five biotinylated RNA fragments (F1: 1–1215 nt; F2: 1–590 nt; F3: 1–840 nt; F4: 841–1215 nt; F5: 591–840 nt; F6: full‐length antisense) for pull‐down experiments in breast cancer cell lysates. The gene discussed is YBX1; the disease is breast cancer.