YBX1 belongs to the RBP family and is a multifunctional oncoprotein involved in various biological processes, including DNA repair, pre‐mRNA splicing, mRNA transcription, stability, and regulation of translation.[24] It is widely implicated in cancer cell proliferation, aging, and drug resistance processes.[25] Recent studies have shown that YBX1 is significantly overexpressed in breast cancer and plays a crucial role in promoting tumor progression.[26, 27, 28] Kaplan‐Meier survival analysis revealed that elevated YBX1 expression is associated with poor prognosis in breast cancer patients. The gene discussed is YBX1; the disease is cancer.