Notably, genes involved in immediate-early responses (e.g., EGR1, FOS, JUNB, NR4A1) and stress response (e.g., CRYAB, BTG2, GADD45G, HSPB3) exhibited increased expression in IHD, reflecting cellular adaptations to ischemic stress. The gene discussed is GADD45G; the disease is myocardial ischemia.