WGS analysis for structural variants suggested 107 AML-associated oncogenic or likely oncogenic fusions in 106 cases (SJ031259 harbored both CBFB::MYH11 and a CNTRL::KIT fusion), of which 97 were predicted to produce fusion oncogenes/chimeric oncoproteins and 10 were suspected to be enhancer-hijacking structural alterations that activate adjacent oncogenes (Fig. 2). Here, MYH11 is linked to acute myeloid leukemia.