STING1 and neoplasm: In the BeatAML database, the results showed a strong negative correlation between STING expression and IFN-γ, Merck18 (T-cell-inflamed signature), CD274, CD8, and T-cell dysfunction-score signatures, whereas a strong positive correlation was observed between STING expression and T-cell exclusion signatures, including exclusion, and the M2 subtype of tumor-associated macrophages (TAMs) (Figure 5A).