In chronic lymphocytic leukemia (CLL), STING expression was negatively correlated with stromal-related signatures such as endothelium (r = −0.52, P < 0.001), cancer-associated fibroblast (CAF) (r = −0.58, P < 0.001), matrix (r = −0.67, P < 0.0001), matrix remodeling (r = −0.56, P < 0.0001), and protumor cytokines (r = −0.63, P < 0.0001). Here, STING1 is linked to cancer.