CIITA and acute myeloid leukemia: Our study found that these immunosuppression-related SNPs are indeed related to the different occurrence, development, and treatment processes of AML, such as CD163 rs4883263 is associated with AML susceptibility, abnormal chromosome karyotype, and low PLT count at diagnosis; CD200 rs2272022 is a protective factor against low PLT count; CIITA rs4780335 is associated with high WBC count at diagnosis and poor OS; LILRB4 rs1048801 is associated with poor AML treatment response and poor OS, respectively.