Specifically, we identified the Cholesterol Homeostasis (p.adj = 0.0380), Inflammatory Response (p.adj= 0.0429), IL2 STAT5 signaling (p.adj = 0.0380), TNFa Signaling via NFKB (p.adj = 0.0429), Angiogenesis (p.adj = 0.0.0638), Coagulation (p.adj = 0.0606), KRAS Signaling Up (p.adj = 0.0453), Interferon Gamma Response (p.adj = 0.0453), IL6 JAK STAT3 Signaling (p.adj = 0.0825), Xenobiotic Metabolism (p.adj = 0.0543), P53 Pathway (p.adj = 0.0380), and Allograph rejection (p.adj = 0.0825) were enriched in the AD microglial cell population. The gene discussed is IL6; the disease is Alzheimer disease.