TNF and Alzheimer disease: Specifically, we identified the Cholesterol Homeostasis (p.adj = 0.0168), TNFa Signaling via NFKB (p.adj = 0.0168), IL2 STAT5 Signaling (p.adj = 0.0316), Angiogenesis (p.adj = 0.0718), Inflammatory Response (p.adj = 0.0560), P53 Pathway (p.adj = 0.0664), Interferon Alpha Response (p.adj = 0.0836), and Xenobiotic Metabolism (p.adj = 0.0560) were identified in the AD microglial cell population.