For example, PC3 and sPC3 shared significant enrichment (p.adj < 0.1) of the Cholesterol Homeostasis, Inflammatory Response, IL2 STAT5 signaling, TNFa Signaling via NFKB, Angiogenesis, P53 Pathway, Interferon Alpha Response, and Xenobiotic Metabolism pathways in the AD microglial populations. The gene discussed is TNF; the disease is Alzheimer disease.