TP53 and Alzheimer disease: For example, PC3 and sPC3 shared significant enrichment (p.adj < 0.1) of the Cholesterol Homeostasis, Inflammatory Response, IL2 STAT5 signaling, TNFa Signaling via NFKB, Angiogenesis, P53 Pathway, Interferon Alpha Response, and Xenobiotic Metabolism pathways in the AD microglial populations.