OPRK1 and Alzheimer disease: In contrast, PK-11195 (ρ=−0.3194, q=0.0203), a benzodiazepine receptor antagonist (TSPO), Torin-2 (ρ=−0.3223, q=0.0261), an MTOR inhibitor (MTOR), and Salvinorin-A (ρ=−0.426, q=9.39E-05), an opioid receptor agonist (OPRK1) exhibited similar signatures to AD (Figure 6C).