For example, DEXA-NR3C1-FOXP3-VIM, DEXA-NR3C1-FOXP3-NFKBIA and DEXA-NR3C1-FOXP3-BTG2 pathways are distinct in Tregs, reflecting their specialized role in immune suppression under inflammatory conditions like COVID-19. Here, FOXP3 is linked to COVID-19.