LRMDA and melanoma: In agreement with the previous studies on RAB32 and LRMDA, we could observe a decrease in pigmentation in RAB32 CRISPR/Cas9 knock-out human melanoma MNT1 cells (Figure 4F-H), as well as in a previously characterised LRMDA knock-out MNT1 cell line (Figure 4I-J) (Beyers et al., 2022).