LRMDA and infection: Similarly, LRMDA has been implicated in a variety of disease conditions that appear to be un-related to melanosome biogenesis: a SNP (rs10824307) near LRMDA is associated with mild-obesity-related diabetes (Mansour Aly et al., 2021), and as highlighted previously (Beyers et al., 2022), at least two OCA7 patients harboring LRMDA mutations have recurrent infections (Kilic et al., 2021).